The greatest benefit of InertCore C18 is the trusted long-term reproducibility. Many core shell columns in the market often suffer from batch-to-batch or lot-to-lot reproducibility issues which makes it difficult for researchers to employ in their critical method development. GL Sciences successfully developed the packing material of InertCore C18 from scratch. The whole entire manufacturing and production of the packing material, bonding of the stationary phase and packing of the column are executed within GL Sciences. GL Sciences truly believes that this system is the only way to provide trusted long-term reproducible core shell columns to support method developers who expects columns to maintain performance over the lifetime of their method.