TSKgel PWxl-, PW- and SuperMultiporePW-type columns are the columns of choice for the analyses of water-soluble polymers. All TSKgel polymer-based gel filtration columns are prepared from polymethacrylate resin. The smaller particle size TSKgel PWxl-type resins have a higher % crosslinking than PW-type columns to allow for operation at higher back pressure. TSKgel PWxl-, PW- and SuperMultiporePW-type columns can be used from pH 2 to 12 with water or buffer (up to 20% methanol/80% aqueous) as eluent. TSKgel PWxl-, PW- and SuperMultiporePW-type columns can be operated up to 80°C (50°C for TSKgel G-DNA-PW). The TSKgel G6000PW column is also available in PEEK hardware for ultra-low sample adsorption when analyzing viruses. The TSKgel SuperOligoPW column is more hydrophilic than the TSKgel G-Oligo-PW column. Use higher efficiency TSKgel PWxl-type columns for optimal resolution, to reduce analysis time, or in sample limited applications. Use TSKgel PW-type columns when analysis time is not critical, when sample mass is not limited, to collect fractions, or to obtain maximum number of plates (at the expense of analysis time). TSKgel SuperMultiporePW columns are packed with particles containing a wide range of pore sizes. Semi-micro SuperMultiporePW columns span a wide separation range from high MW polymers to oligomers.