Zenix-C

Zenix™-C SEC phase, developed based on innovative surface coating technology, comprises of uniform, hydrophilic, and neutral nanometer thick film chemically bonded to high purity and mechanically stabilized silica. Zenix™-C, uses lay-down monolayer on porous silica as oppose to Zenix of stand-up monolayer (as shown below), offers ideal phase chemistry for hydrophobic samples like insulin, membrane protein monoclonal antibodies derivatized with polymer branches (polypeptide or PEG) separation. The 3µm based packing material allows for high resolution and performance separation.

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Zenix-C

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Stationary Phase Structure Illustration and Comparison

Phase structure difference: a monolayer stands up on the silica surface for SRT® and Zenix™, and a monolayer lays down on the silica surface for SRT®-C and
Zenix™-C.

Product Line	SRT®	Zenix™	SRT®-C	Zenix™-C
Particle size	5 µm	3 µm	5 µm	3 µm
Pore size (Å)	100, 150, 300, 500, 1000 & 2000	80, 100, 150, 300	100, 150, 300, 500, 1000 & 2000	80, 100, 150, 300
Resolution	High	Highest, Short column for faster separation	High	Highest, Short column for faster separation
Efficiency	High	Doubled from 5µm	High	Doubled from 5µm
Selectivity	Same for SRT® and Zenix™	Same for SRT®-C and Zenix™-C
Surface structure	Chemically bonded stand-up monolayer	Chemically bonded lay-down monolayer
Recommended Sample Types	Monoclonal antibodies, proteins, peptides, nucleic acids, oligonucleotides, virus, and water-soluble polymers	""Tough samples"" such as hydrophobic proteins like insulin, membrane protein monoclonal antibodies derivatized with polymer branches, e.g. polypeptide, PEG.

Ideal for separation and analysis of hydrophobic proteins, and monoclonal antibodies derivatized with polymer branches such as polypeptide or PEG
Particle size of 3 µm
Selection of pore size: 100, 150 and 300 Å
Highest separation efficiency and resolution
High capacity
High lot-to-lot reproducibility
High protein recovery with intact biological activity