Zenix-C

Zenix™-C SEC phase, developed based on innovative surface coating technology, comprises of uniform, hydrophilic, and neutral nanometer thick film chemically bonded to high purity and mechanically stabilized silica. Zenix™-C, uses lay-down monolayer on porous silica as oppose to Zenix of stand-up monolayer (as shown below), offers ideal phase chemistry for hydrophobic samples like insulin, membrane protein monoclonal antibodies derivatized with polymer branches (polypeptide or PEG) separation. The 3µm based packing material allows for high resolution and performance separation.

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Zenix-C

Zenix™-C SEC phase, developed based on innovative surface coating technology, comprises of uniform, hydrophilic, and neutral nanometer thick film chemically bonded to high purity and mechanically stabilized silica. Zenix™-C, uses lay-down monolayer on porous silica as oppose to Zenix of stand-up monolayer (as shown below), offers ideal phase chemistry for hydrophobic samples like insulin, membrane protein monoclonal antibodies derivatized with polymer branches (polypeptide or PEG) separation. The 3µm based packing material allows for high resolution and performance separation.

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Stationary Phase Structure Illustration and Comparison

Phase structure difference: a monolayer stands up on the silica surface for SRT® and Zenix™, and a monolayer lays down on the silica surface for SRT®-C and
Zenix™-C.

Product Line SRT® Zenix™ SRT®-C Zenix™-C
Particle size 5 µm 3 µm 5 µm 3 µm
Pore size (Å) 100, 150,
300, 500,
1000 &
2000
80, 100, 150,
300
100, 150, 300,
500, 1000 & 2000
80, 100, 150, 300
Resolution High Highest, Short
column for
faster
separation
High Highest, Short column for
faster separation
Efficiency High Doubled from
5µm
High Doubled from 5µm
Selectivity Same for SRT® and Zenix™ Same for SRT®-C and Zenix™-C
Surface structure Chemically bonded stand-up monolayer Chemically bonded lay-down monolayer
Recommended
Sample Types
Monoclonal antibodies,
proteins, peptides, nucleic
acids, oligonucleotides, virus,
and water-soluble polymers
""Tough samples"" such as hydrophobic proteins
like insulin, membrane protein monoclonal
antibodies derivatized with polymer branches,
e.g. polypeptide, PEG.
  • Ideal for separation and analysis of hydrophobic proteins, and monoclonal antibodies derivatized with polymer branches such as polypeptide or PEG
  • Particle size of 3 µm
  • Selection of pore size: 100, 150 and 300 Å
  • Highest separation efficiency and resolution
  • High capacity
  • High lot-to-lot reproducibility
  • High protein recovery with intact biological activity